Mặc dù thế hệ các chipset cũ vẫn hỗ trợ Ryzen đời mới tuy nhiên để trải nghiệm những công nghệ mới nhất như PCIe 4 thì chỉ những chipset đời mới như X570 mới hỗ trợ

• Asus ROG Crosshair VIII Formula (ATX)
• Asus ROG Crosshair VIII Hero (Wi-Fi) (ATX)
• Asus ROG Crosshair VII Hero (ATX)
• Asus ROG Crosshair VIII Impact (Mini DTX)
• Asus ROG Strix X570-E Gaming (ATX)
• Asus ROG Strix X570-F Gaming (ATX)
• Asus ROG Strix X570-I Gaming (Mini ITX)
• Asus TUF Gaming X570-Plus (Wi-Fi) (ATX)
• Asus TUF Gaming X570-Plus (ATX)
• Asus Prime X570-Pro (ATX)
• Asus Prime WS X570-ACE (ATX)

• GIGABYTE X570 AORUS XTREME
• GIGABYTE X570 AORUS ELITE
• GIGABYTE X570 AORUS ULTRA
• GIGABYTE X570 AORUS PRO WIFI
• GIGABYTE X570 I AORUS PRO WIFI (Mini-ITX)
• GIGABYTE X570 AORUS PRO

• MSI MEG X570 Godlike
• MSI MEG X570 ACE
• MSI MPG X570 Gaming Pro Carbon WiFi
• MSI MPG X570 Gaming Edge WiFi
• MSI MPG X570 Gaming Plus
• MSI Prestige X570 Creation
• MSI X570-A Pro

• ASRock X570 Taichi
• ASRock X570 Extreme4
• ASRock X570 Pro4
• ASRock X570 Pro4 R2.0
• ASRock X570M Pro4
• ASRock X570M Pro4 R2.0
• ASRock X570 Phantom Gaming X
• ASRock X570 Phantom Gaming 6
• ASRock X570 Phantom Gaming 4